Human Health | Test and Evaluation
Human Exposure Toxicology
Analytical and bioanalytical testing services for a wide variety of consumer products
Consumer Products Safety
How safe are the products you use? Every year, an estimated 2,000 new chemicals are introduced into the consumer products we use daily, and there is little to no toxicological data regarding their safety for use.
MRIGlobal toxicology experts provide analytical chemistry services to advance the mission of promoting human health through science-based evaluation of toxicological information. For this critical public health function, MRIGlobal examines chemicals (such as industrial chemicals, prescription drugs, consumer product additives, personal care products, nutritional supplements, and natural products) for characteristics that could cause cancer, genetic defects, or immune system responses.
MRIGlobal is in the drug-testing business.
We analyze human and animal plasma and tissue to determine the chemical(s) in those samples. If your clinic is doing an analysis on the amount of drug in any given sample or needs to see how a particular drug interacts with medical countermeasures, we can help.
We approach bioanalytical method validation and sample analysis with strict adherence to quality control assessment, such as routine use of system blanks and matrix evaluation precision and accuracy samples. Preliminary studies may be conducted as non-GLP followed by definitive GLP studies with all requisite parameters.
Our work is done in strict accordance with federal regulations, an MRIGlobal area of expertise.
MRIGlobal offers chemical characterization; test article formulation preparation and analysis; and bioanalytical method validation and sample analysis for parent test article and possible metabolites. Acute toxicokinetics studies are available.
What We Test
Method development, validation, and analysis of a variety of analytes
GLP method development/transfer and long-term stability studies
Compliance with FDA guidelines
Evaluation of fundamental performance and validation parameters
Quantitation of analytes and metabolites in biological tissue and fluid matrices follows GLP protocols
Our team of analytical chemists and repository specialists are dedicated to advancing our mission to make the world a healthier, safer place to live.
Through our long-standing history, MRIGlobal scientists have presented and published over 45 posters and manuscripts at national and international meetings for work sponsored by the NIH-National Toxicology Program. Examples of our published work include:
Postnatal Effects of Gestational and Lactational Gavage Exposure to Boric Acid
Development and Validation of an Analytical Method to Quantitate Tris(chloroisopropyl)phosphate in Rat and Mouse Plasma
Comparison of phytochemical composition of Ginkgo biloba extracts
- Comparative toxicokinetics of bisphenol S and bisphenol AF in male rats and mice following repeated exposure via feed
Work with us
MRIGlobal looks forward to contributing our expertise where it matters most.
MRIGlobal is your resource for toxicology research. Get started using our Project Quote Tool to learn how we can advance your next project.