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MRIGlobal, with key partners Thermo Fisher Scientific and Arizona State University (ASU), will lead a molecular biodosimetry development program for the Biomedical Advanced Research and Development Authority (BARDA), a division of the Office of the Assistant Secretary for Preparedness Response within the U.S. Department of Health and Human Services. The contract, worth more than $21.3 million over the first four years and three months, could be extended for up to $100 million over 10 years.

The ARad Biodosimetry Test is a diagnostic test designed to determine absorbed doses of ionizing radiation and inform the use of medical countermeasures to administer medical care following a radiation or nuclear incident. The ARad Biodosimetry Test was developed by researchers at ASU’s Biodesign Institute and Thermo Fisher Scientific and is designed to be run in a clinical health care laboratory that produces a quantitative estimate of the actual absorbed dose a person received.

MRIGlobal, with partners Thermo Fisher Scientific and ASU, will clinically test and validate the ARad Biodosimetry Test for FDA clearance. The FDA-cleared test will be manufactured by Thermo Fisher Scientific and stockpiled for available testing.

Using the ARad Biodosimetry Test, blood samples will be analyzed for up to seven days post exposure to measure how genes respond to different amounts of radiation, and the test is expected to generate results in approximately eight hours. This test provides rapid response capabilities and high throughput sample analysis with the potential to process 400,000 or more tests a week.